Approved Anti-Cancer Drugs Reveal New Target: Non-Coding RNAs Scientists at The Scripps Research Institute and the California Institute for Biomedical Research (CALIBR) have found that some types of small-molecule drugs, including marketed anticancer drugs, may work in part by binding to disease-related noncoding RNAs. Their discovery could open up new avenues of research for developing small-molecule drugs against what are …

Targeting Cilia Could Offer Universal Approach to Combat Anticancer Drug Resistance Scientists in the U.K. have identified a potentially universal way to resensitize drug-resistant cancer cells to therapy, by targeting the cells’ cilia. The Institute of Cancer Research (ICR) team found that cells with either acquired or de novo resistance to kinase inhibitors are characterized by increased numbers and/or longer …