Application note: Monitoring receptor ligand binding in living cells In this application we will show how a cAMP BRET biosensor can be used to monitor ligand binding with the help of the CLARIOstar microplate reader… A number of assay techniques are used to study ligand binding to GPCRs in living cells. The most well-known being the use of radioactively labelled …

Improving nanotube biosensors for implantable sensing (Nanowerk News) EPFL scientists have developed new nanotube biosensors using synthetic biology, which improves their sensing capabilities in complex biofluids, such as blood and urine. The study is published in the Journal of Physical Chemistry Letters (“Xeno nucleic acid nanosensors for enhanced stability against Ion-Induced Perturbations”). Biosensors are devices that can detect biological moleculesin …

Innovative Light-Delivery Technique Improves Biosensors Microdisks are a type of microscale resonator that use the whispering-gallery optical effect to confine and enhance light that enters the disk. Just as the curved walls of a whispering gallery carry sound waves to allow whispers to be clearly heard across a room, the curved inner surface of a microdisk carries light waves across …

Measuring sweat in wearable biosensing devices When people sweat, they unknowingly release a wide range of chemicals that can noninvasively inform clinicians on anything from stress hormone levels to glucose. But it’s hard for researchers to glean this information — unless you sweat a lot. Emerging wearable devices using stimulant gels have provided a way to induce sweat locally on …