Variant of the p53 Gene Increased Tumor Cell Metabolism Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant. TP53 is the most frequently mutated gene in human …

A new weapon against bone metastasis? VIDEO: YIBIN KANG OF PRINCETON UNIVERSITY HAS DEVELOPED AN ANTIBODY THAT FIGHTS BONE METASTASIS BY UNDERMINING CANCER’S DEFENSE STRATEGY AND ALLOWING CHEMOTHERAPY TO WORK. THIS 3-D FLUORESCENT IMAGE SHOWS CANCER’S DEFENSE… view more  CREDIT: COURTESY OF KANG LAB/PRINCETON UNIVERSITY In the ongoing battle between cancer and modern medicine, some therapeutic agents, while effective, can bring undesirable or …