medical biotechnologyProtein discovery may explain why patients develop resistance to new anti-cancer drugsProtein discovery may explain why patients develop resistance to new anti-cancer drugs A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication. In a study published in Nature Cell Biology, the team from …ادامه مطلب
medical biotechnologyResearchers use silicon nanoparticles for bioimaging and drug deliveryResearchers use silicon nanoparticles for bioimaging and drug delivery (Nanowerk News) An international research team has studied a new cell visualisation and drug delivery system based on nanoparticles coated with luminescent dye molecules. Scientists have found out that the particle material and the distance between the dye and the particle’s surface affect the intensity of the luminescent signal. It turned …ادامه مطلب
medical biotechnologyTwo-pronged antibodies draw immune killers directly to cancer cellsTwo-pronged antibodies draw immune killers directly to cancer cells JUPITER, FL–May 30, 2018–Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In the lab of biochemist and immunologist Christoph Rader, PhD, associate professor at The Scripps Research Institute in Florida, scientists have engineered a new type of …ادامه مطلب
medical biotechnologySmall-Molecule RNA-Targeting Technology Kills Cancer CellsSmall-Molecule RNA-Targeting Technology Kills Cancer Cells Scientists at The Scripps Research Institute have developed a small molecule-based RNA-editing tool that can selectively delete RNA targets associated with diseases such as cancer. Offering a potential alternative to CRISPR-Cas9–based tools that edit DNA, the new technology, developed by Matthew D. Disney, Ph.D., attaches an RNA-targeting, drug-like molecule to an RNA-degrading enzyme. Because …ادامه مطلب
medical biotechnologyNew data changes the way scientists explain how cancer tumors developNew data changes the way scientists explain how cancer tumors develop Researchers led by scientists at The University of Texas Medical Branch at Galveston and Baylor College of Medicine found that a losing a section of messenger RNA that was previously thought to transform normal cells into cancerous ones actually acts by blocking a body’s ability suppress the formation of …ادامه مطلب
medical biotechnologyCancer’s DNA Repair Deficiency Origins Become ClearerCancer’s DNA Repair Deficiency Origins Become Clearer The link between cancer mutations and DNA repair mechanisms has been well established. However, the specific origins of the mutation in these essential pathways have remained enigmatic. Now, researchers at the European Bioinformatics Institute (EMBL-EBI), the University of Dundee, and the Wellcome Sanger Institute have utilized human and worm data to explore the …ادامه مطلب
medical biotechnologySenti launches to improve cell therapies with synthetic gene circuitsSenti launches to improve cell therapies with synthetic gene circuits Building circuits isn’t common in biotech labs, particularly labs developing cell-based therapies for cancer. Tim Lu, who studied computer science and electrical engineering as an undergraduate before going to medical school, wants to change that. But rather than build electronic circuits out of silicon, Lu, now a professor at MIT, …ادامه مطلب
medical biotechnologyKite, Sangamo Launch Up-to-$3B+ Cancer Cell Therapy PartnershipKite, Sangamo Launch Up-to-$3B+ Cancer Cell Therapy Partnership Kite, a Gilead Company, will use Sangamo Therapeutics’ zinc finger nuclease (ZFN) gene-editing technology platform in a global oncology cell therapy collaboration that could generate up to $3.16 billion-plus for Sangamo, the companies said today. Kite plans to modify genes through Sangamo’s ZFN technology in order to develop autologous and allogeneic next-generation …ادامه مطلب
medical biotechnologyبهبود لوسمی کودکان توسط غربالگریNew cancer cell screening is improving childhood leukaemia treatment A study has shown that current methods used to determine the correct level of chemotherapy required for each young patient may be improved by looking at the genetic make-up of the child’s cancer cells. Findings have already led to changes to treatment tailoring for newly diagnosed children, with around half of youngsters with …ادامه مطلب
