medical biotechnologyCell and Gene Therapy Tracker: Global CAR T-Cell TrialsCell and Gene Therapy Tracker: Global CAR T-Cell Trials With our partners at CellTrials.org, we’ve developed an interactive map that displays the numbers of CAR T-cell trials taking place in countries across the world. Trials are categorized as targeting either hematologic malignancies or solid tumors. Click a country on the map to access the data on trials occurring there or …ادامه مطلب
medical biotechnologyNSW Health Funds Indee Labs’ First Preclinical Study Into Gene-Modified Cell Therapy Manufacturing for Blood CancerNSW Health Funds Indee Labs’ First Preclinical Study Into Gene-Modified Cell Therapy Manufacturing for Blood Cancer This preclinical study will pave the way for biopharmaceutical companies to transition away from using viruses. The aim is to enable gene-modified cell therapy manufacturing with open source biology to provide patients with improved access to curative therapies for blood cancer. August 09, 2018 …ادامه مطلب
medical biotechnologyVersatile nanospheresVersatile nanospheres (Nanowerk News) How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich (TUM) and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue …ادامه مطلب
medical biotechnologyPatient Registries to Bolster Cell- and Gene-Therapy Clinical Trial DataPatient Registries to Bolster Cell- and Gene-Therapy Clinical Trial Data Due to advances in rare-disease research and individualized cell and gene therapies, there has been a recent crop of treatments approved by regulatory agencies not based on the “gold standard” randomized, controlled, Phase 3 clinical trial. Rather, drug companies are getting products on the market from small, Phase 2 trials …ادامه مطلب
کریسپرCRISPR “One Shot” Cell Therapy for Hemophilia DevelopedCRISPR “One Shot” Cell Therapy for Hemophilia Developed Scientists at the Salk Institute have combined CRISPR-Cas9 gene editing with stem cell technology to generate a one-time, autologous cell therapy for the genetic blood clotting disorder hemophilia B. In vivo tests showed that gene-edited, stem cell–derived liver cells remained viable and functional in hemophiliac mice for nearly a year, after just …ادامه مطلب
medical biotechnologyNEA powers next-generation cell and gene therapy startup Senti to $53M series A roundNEA powers next-generation cell and gene therapy startup Senti to $53M series A round New Enterprise Associates (NEA) has led a $53 million bet on the future of cell and gene therapies. The series A round sets up JLABS resident Senti Biosciences to use advances in synthetic biology to create more targeted, controllable therapies than are advancing down clinical pipelines …ادامه مطلب
medical biotechnologySenti launches to improve cell therapies with synthetic gene circuitsSenti launches to improve cell therapies with synthetic gene circuits Building circuits isn’t common in biotech labs, particularly labs developing cell-based therapies for cancer. Tim Lu, who studied computer science and electrical engineering as an undergraduate before going to medical school, wants to change that. But rather than build electronic circuits out of silicon, Lu, now a professor at MIT, …ادامه مطلب
bioeconomyCell Therapy Developer Rubius Therapeutics Raises $100M MoreRubius Therapeutics said today it has raised $100 million in new financing to further support clinical development and manufacturing of its new red blood cell–derived therapies. The oversubscribed $100 million “crossover” financing brings to more than $220 million the amount of capital raised by the company. In June, Rubius closed on $120 million in a private financing round it said …ادامه مطلب
medical biotechnologyCell Therapy Improves Muscular Dystrophy in More Ways Than OneCell Therapy Improves Muscular Dystrophy in More Ways Than One A genetic disorder that causes progressive muscle degeneration is mostly visible because of the toll it takes on young patients, who eventually lose their ability to walk. However, the disorder, called Duchenne muscular dystrophy (DMD), also affects another muscle that’s not so visible: the heart. Most people with DMD lose …ادامه مطلب
medical biotechnologyModification of CRISPR guide RNA structure prevents immune response in target cellsModification of CRISPR guide RNA structure prevents immune response in target cells CRISPR-mediated genome editing has become a powerful tool for modeling of disease in various organisms and is being developed for clinical applications. Preassembled Cas9 ribonucleoproteins (RNPs) composed of the recombinant Cas9 protein and in vitrotranscribed (IVT) guide RNA complexes can be delivered into cells without risk of foreign …ادامه مطلب
اخبار زیست فناوری | انگلیسیتقویت سلول درمانی توسط آنتی اکسیدان جدیدCell-based therapy success could be boosted by new antioxidant Cell therapies being developed to treat a range of conditions could be improved by a chemical compound that aids their survival, research suggests. Lab tests found that the man-made molecule – a type of antioxidant – helps to shield healthy cells from damage such as would be caused when they are …ادامه مطلب
اخبار زیست فناوری | انگلیسیبهبودی کامل بیماری CLL Personalized cell therapy combination achieves complete remission in CLL patients PHILADELPHIA – Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn’s Abramson Cancer Center (ACC). …ادامه مطلب
